Docetaxel cardiomyopathy
WebNov 10, 2024 · The aim of this study is designed to evaluate the safety, tolerability, pharmacokinetics and preliminary antitumor activity of docetaxel for injection (albumin-bound) in different dose regimens in patients with advanced solid tumors. Detailed Description: This study will be conducted in two stages. WebFeb 20, 2024 · Not only can people develop cancer treatment-related cardiac dysfunction (CTRCD)—the decreased ability of the left ventricle to pump blood effectively, which may lead to heart failure —they can also develop any number of other heart problems including hypertension, arrhythmia, inflammation of the pericardium (the sac-like membrane …
Docetaxel cardiomyopathy
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WebSymptoms of heart problems related to cardiotoxicity may include: Abdomen enlargement ( abdominal distension ). Chest pain. Dizziness. Heart palpitations. Shortness of breath (dyspnea). Swelling and fluid retention ( edema) in the legs. What causes cardiotoxicity? Certain cancer treatments may cause cardiotoxicity, including: WebDocetaxel (Taxotere; Rhône-Poulenc Rorer, Antony, France) is one of the most promising drugs that has emerged in recent years, with phase II studies in previously …
WebFeb 9, 2009 · Docetaxel/cyclophosphamide (TC) is favored left of 1. AC, doxorubicin/cyclophosphamide; ER, estrogen receptor; PR, progesterone receptor. Fig 3. … WebCardiotoxicity is heart damage that arises from certain cancer treatments or drugs. It can develop years after cancer treatment, especially in adults who received cancer …
WebJun 6, 2016 · In summary, HER2-targeted therapies have transformed treatment options in breast cancer. HER2 is expressed in tumor cells and also in cardiomyocytes, leading to cardiac dysfunction when these … WebApr 2, 2024 · Cardiomyopathy (kahr-dee-o-my-OP-uh-thee) is a disease of the heart muscle that makes it harder for the heart to pump blood to the rest of the body. Cardiomyopathy can lead to heart failure. The main types …
WebJul 1, 2024 · Takotsubo cardiomyopathy, also known as stress cardiomyopathy, is a clinical syndrome that generally presents as chest pain mimicking acute coronary syndrome or as an acute heart …
WebSep 15, 2005 · This study will test whether giving a combination of a vaccine together with docetaxel is more effective against breast cancer than docetaxel alone. The Food and Drug Administration has approved docetaxel to treat many cancers, including breast cancer. ... Clinically significant cardiomyopathy requiring treatment; Chronic hepatitis … botanical artwork printsWebCardiomyopathy is found among people who take Taxotere, especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months ... Taxotere has active ingredients of docetaxel. It is often used in breast cancer. eHealthMe is studying from 61,077 Taxotere users for its effectiveness, alternative drugs and more. ... hawley shoes in shelton ctWebDec 8, 2010 · This is a randomised, double-blind placebo controlled phase 2 trial. Patient will be randomly assigned 1:1 between 2 treatment arms. They will receive either docetaxel 75mg/m2 IV and placebo given bd, or AZD6244 75mg bd daily with docetaxel 75mg/m2 IV. Docetaxel will be administered every 3 weeks for a maximum 6 cycles, but … hawley shoes stamford ctWebDocetaxel Female Humans Middle Aged Paclitaxel / adverse effects* Paclitaxel / analogs & derivatives Skin Neoplasms / secondary Taxoids* Ventricular Dysfunction, Left / … hawleys homebred reptileshawley shooting clubWebCardiotoxicity rates of other HER2-targeted treatments, such as pertuzumab, T-DM1, lapatinib, neratinib, tucatinib, trastuzumab deruxtecan, and margetuximab, appear to be significantly lower as reported in the pivotal trials which led to their approval. botanical assessmentWebMar 10, 2024 · RT to the chest wall and mediastinum leads to a plethora of cardiac complications including constrictive and restrictive … botanical astrology