Ghmp kinase family protein
WebApr 30, 2015 · In GHMP family, HSK is the first structurally identified protein kinase divided into two globular domains whose secondary structure being similar to elongation factor … WebPhosphomevalonate kinase, peroxisomal; GHMP kinase family protein; Its function is described as kinase activity, ATP binding; Involved in phosphorylation; Expressed in 24 plant structures; Expressed during 15 growth stages; Contains the following InterPro domains: Phosphomevalonate kinase, eukaryotic (InterPro:IPR005916), …
Ghmp kinase family protein
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WebMevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of this gene results in mevalonic aciduria, a disease characterized psychomotor retardation, failure to thrive, hepatosplenomegaly, anemia and recurrent febrile crises. WebMar 15, 2002 · Analysis of the MVK model in the context of the other members of the GHMP kinase family offers the opportunity to understand both the mechanism of these …
WebMevalonate kinase, also known as MVK, belongs to the GHMP kinase family. Mevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of this gene results in mevalonic aciduria, a disease characterized psychomotor retardation, failure to thrive ... WebMar 5, 2024 · The protein encoded by this gene belongs to the GHMP (galacto-, homoserine, mevalonate and phosphomevalonate) kinase family and catalyzes the phosphorylation of L-fucose to form beta-L-fucose 1-phosphate. This enzyme catalyzes the first step in the utilization of free L-fucose in glycoprotein and glycolipid synthesis. L …
WebGene ID: 820249, updated on 8-Nov-2024 Summary Encodes a GHMP kinase family protein that acts as a galacturonic acid-1-phosphate kinase that catalyzes the production of galacturonic acid-1-phosphate. This is a precursor of the important cell wall building block UDP-galacturonic acid. WebGHMP kinase family protein; Sugar-1-kinase with a strict substrate specificity for D-glucuronic acid and ATP. Involved in the biosynthesis of UDP- glucuronic acid (UDP-GlcA), providing nucleotide sugars for cell- wall polymers. May be also involved in a salvage pathway for glucuronic acid (By similarity)
http://pfam-legacy.xfam.org/family/PF09109
WebNov 23, 2004 · The sequences and three-dimensional structures of the galactokinase, homoserine kinase, mevalonate kinase, and phosphomevalonate kinase (GHMP) family were compared to identify highly conserved surface residues. The functions of these solvent-accessible residues were assessed by determining the effec … austin elliott madison mshttp://pfam-legacy.xfam.org/family/PF00288.29 gansu köket menyWebDec 15, 2000 · Background: Homoserine kinase (HSK) catalyzes an important step in the threonine biosynthesis pathway. It belongs to a large yet unique class of small metabolite … austin ellis attorneyWebMitogen-activated protein kinases (MAPKs) are important components of the tripartite mitogen-activated protein kinase signaling cascade and play an important role in plant growth and development. Although members of the MAPK gene family have been identified in model plants, little information is available regarding this gene family in fruit crops. gant baz 5WebProtein: KIME_HUMAN Mevalonate kinase. FUNCTION: May be a regulatory site in cholesterol biosynthetic pathway. CATALYTIC ACTIVITY: ATP + (R)-mevalonate = ADP + (R)-5- phosphomevalonate. ... SIMILARITY: Belongs to the GHMP kinase family. Mevalonate kinase subfamily. SEQUENCE CAUTION: Sequence=CAA53059.1; … gant amazonWebFeb 1, 2007 · The GHMP kinases which in 1993 firstly identified by protein sequence alignment in the form of sugar kinase (Bork et al. 1993; Timson 2007) are a structurally … ganoderma gyerekeknekWebJul 28, 2024 · Due to high mobility in these motifs, very high levels of B factors are often recorded not only in HSK but also in other members of GHMP Kinase family members [65, 68,69,70]. Krishna et al. [ 53 ] proposed that the closed state of an enzyme is maintained by an effective salt bridge formed between Arg-187 and Asp-23 in crystallographic studies ... austin elliott harris