How does phenytoin cause gingival hyperplasia
WebFeb 2, 2024 · In some people, long-term use of phenytoin may cause gingival hyperplasia or overgrowth of gums. The incidence of phenytoin-induced gum overgrowth lies between 3% to 93% . Around 50% of people on ... WebPhenytoin sodium is known to be the most common cause of gingival hyperplasia. 1,4 A minor degree of hyperplasia occurs quite commonly and this generally causes only cosmetic problems, especially for women. However, when phenytoin is used for prolonged periods in high dosage a severe degree of gingival overgrowth occurs.
How does phenytoin cause gingival hyperplasia
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WebGingival hyperplasia was very common in patients taking PHT (16%-94% of patients). Alveolar bone loss occurred in patients taking carbamazepine or PHT. Patients taking valproate, carbamazepine or phenobarbital also had gingival hyperplasia. We found no published studies of newer-generation AEDs. WebThere was a tendency for gingival hypertrophy to be associated with both increasing dosage of phenytoin per unit of body weight and the duration of phenytoin administration. All patients followed had a statistically significant progressive trend to increasing gingival hyperplasia with higher total and free phenytoin concentration. Publication types
WebMay 11, 2014 · Drug-induced gingival overgrowth is frequently associated with three particular drugs: phenytoin, cyclosporin, and nifedipine. As gingival enlargement develops, it affects the normal oral hygiene practice and may interfere with masticatory functions. The awareness in the medical community about this possible side effect of nifedipine is less ... WebThe active drugs lamotrigine, oxcarbazepine, and phenobarbital were significantly associated with gingival overgrowth in 61%, 71%, and 53% of cases, respectively, and …
WebSeveral distinct classes of drugs, such as anticonvulsants, immunosuppressants, and calcium channel blockers, caused gingival overgrowth. One of the main drugs associated … WebSep 19, 2024 · Phenytoin (PHT, or 5,5-diphenylhydantoin), sodium valproate, phenobarbitone, vigabatrin, primidone, mephenytoin, and ethosuximide are some of the drugs that cause gingival hypertrophy. However, phenytoin is the anticonvulsant most associated with gingival enlargements. It is used to treat temporal lobe, tonic-clonic, and …
WebThe most common is chronic inflammatory gingival enlargement, when the gingivae are soft and discolored. This is caused by tissue edema and infective cellular infiltration caused by prolonged exposure to bacterial plaque, and is treated with conventional periodontal treatment, such as scaling and root planing. [1]
WebMar 26, 2024 · Some of the risk factors known to contribute to gingival overgrowth include the presence of gingival inflammation (ie, gingivitis) resulting from poor oral hygiene. … certbot preferred-chainWebThe term “gingival hyperplasia” is inappropriate because enlargement does not result from an increase in the number of cells but rather an increase in extracellular tissue volume with an inflammatory infiltrate of predominantly B lymphocytes. 30 Histologically, in verapamil induced gingival enlargement there is highly vascular connective ... buy studio furniturecertbot pterodactylWebAug 4, 2024 · Symptoms. Gingivitis. Healthy gums are firm and pale pink and fitted tightly around the teeth. Signs and symptoms of gingivitis include: Swollen or puffy gums. Dusky red or dark red gums. Gums that bleed … buy studio in dubaiWebHyperplastic Diseases. Gingival hyperplasia is a simple overgrowth of gum tissue, principally the fibrous submucosa. The hyperplasia can become severe enough to bury incisor teeth ( Fig. 7-40 ). Gingival hyperplasia is most common in brachycephalic dog breeds and is present in 30% of boxer dogs older than 5 years. certbot python2WebKeppra can cause dizziness, fatigue and weakness. Phenytoin (Dilantin): Used for treatment of tonic-clonic seizures and complex partial seizures. Phenytoin will enter breast milk and cross the placenta. Common side effects include ataxia, hypotension, diplopia, nausea and gingival hyperplasia. buy studio gold coastWebOct 30, 2024 · Several distinct classes of drugs, such as anticonvulsants, immunosuppressants, and calcium channel blockers, caused gingival overgrowth. One of … buy studio ghibli films