WebCXCL13 induces the production of secreted phosphoprotein 1 (SPP1 or osteopontin) by macrophages to activate β-catenin and induce an epithelial-to-mesenchymal transition (EMT) phenotype . Deficiency in CXCL13 or CXCR5 significantly suppressed BaP-induced lung cancer in mice, indicating that CXCL13 plays a key role in smohaze carcinogen … Web12 Apr 2024 · Phosphoprotein 1 (SPP1), also known as osteopontin, is a multifunctional secreted phosphorylated glycoprotein. Although SPP1 is produced in a variety of organs, at the cellular level, it is expressed on only a few cell types, such as osteoblasts, fibroblasts, macrophages, dendritic cells, lymphoid cells, and mononuclear cells.
Spp24 is associated with endocytic signalling, lipid ... - PubMed
WebAs pregnancy progresses in women, the uterus can increase 500- to 1000-fold in volume and 24-fold in weight. Therefore, the uterine wall must adapt to increases in fetal growth, ... as well as the ECM proteins secreted phosphoprotein 1 (SPP1, also known as osteopontin (OPN)), FN1, and vitronectin (VTN). WebSecreted phosphoprotein 24 kD (Spp24) is a bone matrix protein that appears to be derived primarily from the liver and delivered to other tissues in a protective complex. A … strathray capital
SPP1 Gene - GeneCards OSTP Protein OSTP Antibody
WebThe 24 kD form of secreted phosphoprotein (SPP-24), a cytokine-binding bone matrix protein with various truncated C-terminal products, is primarily synthesized by the liver. … Web10 Mar 2024 · At Shanghai’s Jiao Tong University School of Medicine, researchers have identified a bone matrix protein called secreted phosphoprotein 24 kD (Spp24) that binds to and neutralizes a protein ... Web6 Feb 2024 · We identified 13 putative effectors secreted by C. trachomatis and 19 secreted by W. chondrophila. ... 24 and 32 h post infection, cells were fixed with ice-cold methanol during 5 min at –20 °C, washed three ... (ii) CPAF, a protein secreted by a Sec-dependent pathway and (iii) the C. trachomatis translocated early phosphoprotein, TepP ... round glass dining table gray