2024 Solubility of gemcitabine hydrochloride

Solubility of gemcitabine hydrochloride

Author: dwhx

August undefined, 2024

WebNov 25, 2024 · The empirical formula for gemcitabine HCl is C 9 H 11 F 2 N 3 O 4 • HCl. It has a molecular weight of 299.66. Gemcitabine HCl is soluble in water, slightly soluble in …

Gemcitabine hydrochloride C9H12ClF2N3O4 - PubChem

WebDec 2, 2013 · The release behavior of another anti-cancer drug gemcitabine from the PU matrix is quite different from that of PTX due to the extreme difference in water solubility between gemcitabine and PTX.PTX is practically insoluble in water, whereas gemcitabine is readily soluble in water and has a solubility of 1.55% [37,67]. WebJun 29, 2024 · Gemcitabine 1 g/m 2 (as 30-minute infusion) has been given on days 1 and 8 of each 21-day cycle; administered in combination with cisplatin (25 mg/m 2 as 1-hour … gas strut recharge

Gemcitabine hydrochloride = 98 HPLC 122111-03-9 - Sigma-Aldrich

http://shiji.cnreagent.com/s/sv273316.html WebBiological Activity for Gemcitabine hydrochloride. Gemcitabine hydrochloride is a deoxycytidine analog that inhibits DNA synthesis. Metabolized to form gemcitabine … WebFeb 25, 2024 · The solution was then diluted 10× with a premade PBS solution of gemcitabine (hydrochloride salt) (12.65 mg/mL). Final concentrations of drugs were 10/1 mg/mL GT. CrEL drug suspensions were used within the same day of preparation due to instability. ... Whether a water soluble gemcitabine (Log P=−1.5) and insoluble paclitaxel ... gas strut murphy bed

Gemcitabine hydrochloride C9H12ClF2N3O4 - PubChem

Gemcitabine (LY-188011) HCl ≥99%(HPLC) - selleckchem

WebGemcitabine hydrochloride (2′-Deoxy-2′,2′-difluorocytidine; dFdC ); >= 98% HPLC; This compound is a featured product for Apoptosis research; Gemcitabine is a widely used … WebGemcitabine is a chemotherapeutic agent used as monotherapy or in combination with other anticancer agents. In combination with [carboplatin], it is indicated for the treatment … gas strut hood supportsWebMar 1, 2024 · One vial contains Gemcitabine hydrochloride equivalent to 200 mg Gemcitabine One vial contains Gemcitabine hydrochloride equivalent to 1000 mg Gemcitabine . After reconstitution, the solution contains 38 mg/ml of Gemcitabine. Excipients: Each 200 mg vial contains 3.5 mg (<1 mmol) sodium. Each 1,000 mg vial … david ortinau github

"WebGemcitabine hydrochloride (2′-Deoxy-2′,2′-difluorocytidine; dFdC ); >= 98% HPLC; This compound is a featured product for Apoptosis research; Gemcitabine is a widely used … " - Solubility of gemcitabine hydrochloride

Solubility of gemcitabine hydrochloride

Gemcitabine hydrochloride = 98 HPLC 122111-03-9 - Sigma-Aldrich

WebJun 1, 2024 · Gemcitabine hydrochloride is soluble in water, slightly soluble in methanol, and practically insoluble in ethanol and polar organic solvents. Gemcitabine for Injection, … WebApr 1, 1999 · Gemcitabine is a fluoro-cytidine analog with primarily antitumor activity and is administered intravenously [120]. Although its hydrochloride salt is well soluble in water …

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WebGemcitabine Hydrochloride is the hydrochloride salt of an analogue of the antimetabolite nucleoside deoxycytidine with antineoplastic activity. … WebGemcitabine, HCl - CAS 122111-03-9 - Calbiochem. View Price and Availability. Supelco. PHR2582. Gemcitabine hydrochloride. Pharmaceutical Secondary Standard; Certified …

WebGeneral description. A bioavailable, moderately toxic, deoxyctytidine analog with anti-metabolite and anti-tumor properties. Shown to be effective against a variety of tumors … WebApr 10, 2024 · Erlotinib’s aqueous solubility is pH-dependent; it is less soluble at neutral pH but more soluble at acidic pH (~ below 5). Erlotinib HCl, marketed under the brand name Tarceva, is prescribed as a single film-coated orally administered tablet at strengths of 25–125. Erlotinib HCL has a maximum solubility of around 0.4 mg/mL at a pH of ~ 2 .

WebGemcitabine hydrochloride is a deoxycytidine analog that inhibits DNA synthesis. Metabolized to form gemcitabine triphosphate (dFdCTP) and gemcitabine diphosphate ... WebSolubility: Soluble in DMSO at 12.5 mg/mL with slight warming; very poorly soluble in ethanol; soluble in water at 25 mg/mL with slight warming; buffers, ... Gemcitabine …

WebJun 1, 2024 · Gemcitabine hydrochloride is soluble in water, slightly soluble in methanol, and practically insoluble in ethanol and polar organic solvents. Gemcitabine for Injection, USP is a sterile white to off-white lyophilized powder and available as 200 mg and 1 g single-dose vials for intravenous use only.

WebGemcitabine prepared as intravenous admixtures of 0.1 and 10 mg/mL as the hydrochloride salt in 5% dextrose injection and 0.9% sodium chloride injection in PVC bags and as a … gas string trimmers ebayWebTest conditions included (1) reconstituted gemcitabine at a concentration of 38 mg/mL as the hydrochloride salt in 0.9% sodium chloride or sterile water for injection in the original … gas strut recharge adelaideWebApr 1, 1999 · Reconstituted gemcitabine as the hydrochloride salt in the original vials is chemically stable at room temperature for 35 days but may develop crystals when stored … gas strut for kitchen cabinet doorWebApplication. It is intended to be used as a USP reference standard in specified quality tests and assays. Also used to prepare standard solutions in the assay and impurities analysis … david ortiz 2013 postseason statsWebUse in Cancer. Gemcitabine hydrochloride is approved to be used alone or with other drugs to treat: Breast cancer that cannot be treated with or that did not respond to … david orthodonticsWebName Gemcitabine hydrochloride Drug Entry Gemcitabine. Gemcitabine is a nucleoside analog and a chemotherapeutic agent. It was originally investigated for its antiviral … david ortiz authentic jerseyWebGemcitabine Hydrochloride, CAS: 122111-03-9, is a deoxycytidine analog that inhibits ribonucleotide reductase & induces apoptosis. ... Gemcitabine Hydrochloride, sc-204763, … david ortiz biography book