Susceptible and resistant mutants
WebPolymorphic variation in susceptibility and metabolism of triclosan-resistant mutants of Escherichia coli and Klebsiella pneumoniae clinical strains obtained after exposure to … S-genes involved in susceptibility to different types of pathogens have been found in many different plant species17,34. Here, S-gene candidates were selected based on the following criteria: pathogen resistance phenotype, being either a single gene or belonging to a small confined gene family in potatoes, each S … See more By applying two guide RNAs, targeted deletions in the gene of interest may be generated22,23. In a study by Čermák el al. 2024, deletions between the … See more StDMR6-1 is a promising S-gene because tetra-allelic mutants not only showed increased late blight resistance (Fig. 1F and Table 3) but also did not differ in over … See more StDMR6-1 and its ortholog SlDMR6-1 are important in pathogen susceptibility (Fig. 1)43 without any obvious growth phenotype (Fig. 3). We investigate the effect … See more
Susceptible and resistant mutants
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WebThe imipenem-selected mutants reduced susceptibility to imipenem gradually, with MIC rising from 0.125 μg/mL to 8 μg/mL. The susceptibility to imipenem was monitored in the presence and absence of the efflux pump inhibitor CCCP in this process. Interestingly, the zone of inhibition was almost constant in the presence of CCCP. WebApr 17, 2012 · The dominant mechanisms of fluoroquinolone resistance identified are 1) chromosomal mutations causing reduced affinity of DNA gyrase and topoisomerase IV for fluoroquinolones and 2) overexpression of endogenous MDR pumps.
WebOct 12, 2024 · The second one, known as MPC, represents a threshold above which the selective proliferation of resistant mutants is expected to occur only rarely . Traditionally, the minimum inhibitory concentration (MIC) has been widely used to determine the susceptibility and resistance of bacteria to antimicrobials. WebJun 13, 2024 · Mutant selection window (MSW) is a collection of concentrations between the MICs of the susceptible and resistant variants. Resistant mutants may be selected …
WebAug 15, 2009 · Though resistance and susceptibility are opposite sides of the same coin, most studies have focused for a long time on the resistance side in search for plant … WebNov 1, 1997 · Silver-resistant mutants were selected by stepwise exposure of silver-susceptible clinical strains of Escherichia coli, two of which did not contain any plasmids, to either silver nitrate or ...
WebIn addition, resistance or susceptibility is relative to and dependent on strain, dose, and route of inoculation of the infectious agent. Various strains of mice are known to differ in their susceptibilities to naturally occurring …
Webthe susceptible strain (blue line) will outcompete the resistant strain (red line). Orange (sub-MIC selective window) and red (traditional mutant selective window) indicate … burlington bridge club williston vtWebAug 1, 2000 · These mutants are resistant to toxin whether made in Bt or E. coli and confer qualitative and quantitative recessive resistance to all aspects of toxicity that we … burlington bridge accidentWebFeb 24, 2024 · Recently, a wheat mlo mutant was shown to be susceptible to the hemibiotrophic fungal pathogen Magnaporthe oryzae, whereas it was still resistant to the obligate biotrophic fungus Blumeria ... burlington bridge commissionWebJul 21, 2011 · Competition experiments between susceptible and resistant strains, streptomycin and tetracycline. Competition experiments at different concentrations of … burlington brindley bath reviewWebAug 24, 2024 · Crops are susceptible to a large set of pathogens including fungi, bacteria, and viruses, which cause important economic losses ( FAO, 2024 ); the enhancement of plant resistance plays an important role in adjusting crop production to meet global population increases. burlington bridge ontarioWebMar 1, 2024 · Acquired resistance in M. tuberculosis was suspected to be due to the selection of resistant mutants because similar mutants were observed in wild-type strains as pre-existing mutants. ... In contrast to rifampicin, there is a close relationship between MICs for the susceptible and resistant populations, ... burlington bridge club vtWebCandidate Ts mutants are re-streaked on two haploid selection media plates, and incubate at 25°C and 37°C. Once the Ts phenotype is confirmed, backcross the MATa Ura + Ts … burlington bristol bridge cost